I'm a professional voice artist and been using Focusrite Scarletts for years, interfaced using USB to my Windows PC. Very easy, very simple.
I'm upgrading and (although I've considered the Clarett 8Pre), I love the ISA preamps - and ideally need 2+ channels to interface into my DAW (Audition).
The 2 channel ISA (the 'Two') doesn't seem to have any AD converter option. The 4 channel ISA (428) does have a digital option using (I believe) 'Dante'.
Assuming I go for the 428, what equipment do I need to:
a) get all 4 channels into my DAW
b) get the full mix out to my external monitors
c) ideally get individual 'outs' into a headphone amp (eg Presonus HP60)
The Scarlett made it all very easy and simple but this step-up to more pro-end equipment has me completely confused.
I'm sorry if this seems a silly question but I can't afford to get it wrong and knew you guys could set me right

Many thanks.
Gus.